Florence, CO has a population of 3,891 and is the 7,570th largest city in the United States. The population density is 891 per sq mi which is 1689% higher than the Colorado average and 883% higher than the national average. The median age in Florence is 37 which is approximately 2% higher than the Colorado average of 36. In Florence, 58% of the population over 15 years of age are married, 98% speak English and 2% speak Spanish. 54% of Florence residents were born in Colorado, 45% were born out of state, 1% were born outside of the United States and 0% were foreign born.