| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 18°F | 35°F | 26°F | 3.0" |
| February | 17°F | 34°F | 25°F | 2.7" |
| March | 25°F | 44°F | 34°F | 2.7" |
| April | 36°F | 59°F | 47°F | 3.6" |
| May | 47°F | 70°F | 58°F | 3.1" |
| June | 57°F | 78°F | 68°F | 4.3" |
| July | 62°F | 82°F | 72°F | 3.4" |
| August | 61°F | 81°F | 71°F | 3.9" |
| September | 54°F | 75°F | 64°F | 4.5" |
| October | 44°F | 63°F | 53°F | 5.2" |
| November | 33°F | 51°F | 42°F | 3.5" |
| December | 25°F | 39°F | 32°F | 4.2" |
| Index | Depew | New York | National |
| Air quality index | 39 | 43 | 42 |
| Pollution index | 1,117,680 | 6,179,275 | 2,726,193 |
| Measurement | Total |
| Days measured | 365 |
| Days with good air quality | 308 |
| Days with moderate air quality | 57 |
| Days w/ poor A.Q. for sensitive groups | 0 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.002% |
| Benzene | 0.010% |
| Carbon Tetrachloride | 0.002% |
| Lead | 0.002% |
| Mercury | 0.001% |
| City | Population | Air Quality Index | National Avg. |
| Clarence Center, NY | 3,211 | 39 | 22.0% |
| Alden, NY | 2,565 | 39 | 22.0% |
| Cheektowaga, NY | 73,457 | 39 | 22.0% |
| Elma Center, NY | 3,806 | 39 | 22.0% |
| Kenmore, NY | 15,081 | 39 | 22.0% |
| Depew, NY | 15,069 | 39 | 22.0% |
| City | Population | Air Quality Index | National Avg. |
| Mastic, NY | 15,068 | 43 | 14.0% |
| St. Augustine, FL | 15,065 | 31 | 38.0% |
| Kenmore, NY | 15,081 | 39 | 22.0% |
| West Park, FL | 15,052 | 41 | 18.0% |
| Hayden, ID | 15,049 | 43 | 14.0% |
| Depew, NY | 15,069 | 39 | 22.0% |
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