AreaVibes reveals the best places to live in Missouri for 2016 using our Livability Score. The Livability Score for each city in Missouri is calculated out of 100 from a unique algorithm based on various metrics, including: amenities, cost of living, crime, education, employment, housing and weather. Missouri has a population of 5,982,413 and a population density of 86.4 people per square mile. The capital city is Jefferson City and the largest city in Missouri is Kansas City. To filter the results, use the dropdown options to sort by population or category.